The neo-Georgian hospital was built between 1918-1920 as one of two tuberculosis sanatoria built and operated by the King Edward VII Welsh National Memorial Association - the other being Talgarth. Llangwyfan Hospital was closed in 1981. The main building is brick and roughcast, with pediment-like gables at either end, and six hipped dormers across its frontage.

Since the 1980s the site has been owned by Mental Health Care Uk, and is now known as Alexander House, Highfield Park.

Source: Edward Hubbard, from `Houses of the Welsh Countryside'
J. Archer, RCAHMW, 27.09.2004